US doctors develop new weight-loss drug

Health Hub staff
Monday, November 14, 2011
A new drug to help you lose weight? Image: Thinkstock

Doctors in the US have developed a new drug which leads to weight loss without dieting or exercise, which has had promising results in animal testing.

Researchers at MD Anderson Cancer Center in Houston gave overweight monkeys a drug called adipotide, a protein compound which targets the blood supply to fat cells and kills them.

After 28 days of daily injections, the monkeys lost an average of 11 percent of their body weight, the US' MSNBC reported.

"It is incredibly exciting, a dream coming true in slow motion," says Dr Wadih Arap, who led the study along with wife Dr Renata Pasqualini.

"Within a few weeks of administering the drug it became clear to us that the efficacy we had seen in rodents was being transplanted to monkeys," said researcher Kristin Barnhart.

"They were getting their waistlines back so we were staring to see the effect. It was such an important milestone for the drug."

After the monkeys returned to their colonies however, they regained the lost weight. Researchers said that although the results were promising, the drug would not be a permanent solution for weight loss, but rather a kick-start for initial weight loss, along with future diet and exercise.

In 2004 drug trials led to substantial weight loss in mice, and after similar results in monkeys the researchers have applied for FDA approval to begin trials in humans, possibly within a year.

The researchers also noticed slight, reversible kidney changes that will need to be monitored closely in human trials.

The study was published in the journal Science Translational Medicine.

User comments
Another drug that can fool people into believing all they have to do is pop a pill and all their troubles will go away, what about good old eating right and exercising... before anyone says I dont know what Im talking about, I do Ive lost weight many times, and believe these pills never show someone how to eat healthy...
hello there i have read your article and i am interested in any updates with the new drug you have for weight loss. could you please email me when you may start doing trials on human testing with it. id like to be one of the people that would like to test it for you, if thats possible as i have gone on so many diets and they have not worked.. i wish to lose at least 3 stone in the next year... so please take me in consideration thanks....
HOPE THE WEIGHT LOSS DRUG WILL LAUNCH IN THE MARKETS OR ANY CHEMIS SHOPS AS SOON AS POSSIBLE AS IT MENTIONED. CAN'T WAIT. AND THIS IS A DREAM COME TRUE FOR EVERYBODY ESPECIALLY FOR FEMALES. A PROMISE.
i so would love to try this new weight loss drug sounds great lol.....


Social media users 'feel jealous': survey

Ask our experts

Should I continue my affair with a married man? Our answer SEX & RELATIONSHIPS EXPERT Dr Gabrielle Morrissey

What's your BMI?

Tools

Body Mass Index Measure your BMI >>Find out if your body is in the healthy body mass index range. Calorie CounterCalorie CounterKeep track of your daily dietary intake. Burn BarometerBurn BarometerHow much exercise should you be doing?